Genes, the serotonergic system and suicidal behavior

Tovilla-Zarate, Carlos Alfonso; Gómez Mendoza, Alma Delia

doi:10.21500/20112084.751

Genes, the serotonergic system and suicidal behavior

Guardado en:

Revista

International Journal of Psychological Research

ISSN

2011-2084

EISSN

2011-7922

Autores

Tovilla-Zarate, Carlos Alfonso

Gómez Mendoza, Alma Delia

Editor

UNIVERSIDAD DE SAN BUENAVENTURA

DOI

10.21500/20112084.751

Volumen

Año de publicación

2012-06-30

Pagina inicial

Pagina final

Pais

Colombia

Licencia

International Journal of Psychological Research - 2012

info:eu-repo/semantics/openAccess

http://purl.org/coar/access_right/c_abf2

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spelling	Genes, the serotonergic system and suicidal behavior Genes, the serotonergic system and suicidal behavior Artículo de revista Anguelova, M., Benkelfat, C., & Turecki, G. (2003). A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior. Molecular Psychiatry, 8(7), 646-653. Arango, V., Underwood, M. D., Gubbi, A. V., & Mann, J. J. (1995). Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims. Brain Research, 688(1-2), 121-133. Asberg, M., Traskman, L., & Thoren, P. (1976). 5-HIAA in the cerebrospinal fluid. A biochemical suicide predictor? Archives of General Psychiatry, 33(10), 1193-1197. Baldessarini, R. J. & Hennen, J. (2004). Genetics of suicide: an overview. Harvard of Review Psychiatry, 12(1), 1-13. Beck, A. T., Weissman, A., Lester, D., & Trexler, L. (1976). Classification of suicidal behaviors. II. Dimensions of suicidal intent. Archives of General Psychiatry, 33(7), 835-837. Bellivier, F., Chaste, P., & Malafosse, A. (2004). Association between the TPH gene A218C polymorphism and suicidal behavior: a meta-analysis. American Journal of Medical Genetics. Part B Neuropsychiatric Genetics, 124B(1), 87-91. https://revistas.usb.edu.co/index.php/IJPR/article/view/751 Inglés https://creativecommons.org/licenses/by-nc-sa/4.0/ International Journal of Psychological Research - 2012 info:eu-repo/semantics/article Universidad San Buenaventura - USB (Colombia) http://purl.org/coar/resource_type/c_6501 info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text International Journal of Psychological Research Publication application/pdf association studies The study of suicidal behavior has gained relevance given that recently about 50% of the population between 14 and 19 years old exhibit suicidal ideation and, in the population in general, there has been a rise of up to 150% in suicidal behavior. The outcomes of these studies of genetic epidemiology show that several genes may be associated with suicidal behavior. In particular, one of the hypotheses propounds that genes of proteins that participate in the serotonergic pathway could be responsible for the development of this behavior. There is neurochemical evidence showing alterations at different levels along this pathway. In this work, a review is made of several of the genes participating in the serotonergic pathway and their possible participation in suicidal behavior. Tovilla-Zarate, Carlos Alfonso Gómez Mendoza, Alma Delia Suicide serotonin Journal article 1 5 genetics polymorphism 58 https://revistas.usb.edu.co/index.php/IJPR/article/download/751/550 2012-06-30 52 https://doi.org/10.21500/20112084.751 10.21500/20112084.751 2012-06-30T00:00:00Z 2011-7922 2012-06-30T00:00:00Z 2011-2084
institution	UNIVERSIDAD DE SAN BUENAVENTURA
thumbnail	https://nuevo.metarevistas.org/UNIVERSIDADDESANBUENAVENTURA_COLOMBIA/logo.png
country_str	Colombia
collection	International Journal of Psychological Research
title	Genes, the serotonergic system and suicidal behavior
spellingShingle	Genes, the serotonergic system and suicidal behavior Tovilla-Zarate, Carlos Alfonso Gómez Mendoza, Alma Delia association studies Suicide serotonin genetics polymorphism
title_short	Genes, the serotonergic system and suicidal behavior
title_full	Genes, the serotonergic system and suicidal behavior
title_fullStr	Genes, the serotonergic system and suicidal behavior
title_full_unstemmed	Genes, the serotonergic system and suicidal behavior
title_sort	genes, the serotonergic system and suicidal behavior
description_eng	The study of suicidal behavior has gained relevance given that recently about 50% of the population between 14 and 19 years old exhibit suicidal ideation and, in the population in general, there has been a rise of up to 150% in suicidal behavior. The outcomes of these studies of genetic epidemiology show that several genes may be associated with suicidal behavior. In particular, one of the hypotheses propounds that genes of proteins that participate in the serotonergic pathway could be responsible for the development of this behavior. There is neurochemical evidence showing alterations at different levels along this pathway. In this work, a review is made of several of the genes participating in the serotonergic pathway and their possible participation in suicidal behavior.
author	Tovilla-Zarate, Carlos Alfonso Gómez Mendoza, Alma Delia
author_facet	Tovilla-Zarate, Carlos Alfonso Gómez Mendoza, Alma Delia
topic	association studies Suicide serotonin genetics polymorphism
topic_facet	association studies Suicide serotonin genetics polymorphism
citationvolume	5
citationissue	1
publisher	Universidad San Buenaventura - USB (Colombia)
ispartofjournal	International Journal of Psychological Research
source	https://revistas.usb.edu.co/index.php/IJPR/article/view/751
language	Inglés
format	Article
rights	https://creativecommons.org/licenses/by-nc-sa/4.0/ International Journal of Psychological Research - 2012 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
references_eng	Anguelova, M., Benkelfat, C., & Turecki, G. (2003). A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior. Molecular Psychiatry, 8(7), 646-653. Arango, V., Underwood, M. D., Gubbi, A. V., & Mann, J. J. (1995). Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims. Brain Research, 688(1-2), 121-133. Asberg, M., Traskman, L., & Thoren, P. (1976). 5-HIAA in the cerebrospinal fluid. A biochemical suicide predictor? Archives of General Psychiatry, 33(10), 1193-1197. Baldessarini, R. J. & Hennen, J. (2004). Genetics of suicide: an overview. Harvard of Review Psychiatry, 12(1), 1-13. Beck, A. T., Weissman, A., Lester, D., & Trexler, L. (1976). Classification of suicidal behaviors. II. Dimensions of suicidal intent. Archives of General Psychiatry, 33(7), 835-837. Bellivier, F., Chaste, P., & Malafosse, A. (2004). Association between the TPH gene A218C polymorphism and suicidal behavior: a meta-analysis. American Journal of Medical Genetics. Part B Neuropsychiatric Genetics, 124B(1), 87-91.
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2012-06-30
date_accessioned	2012-06-30T00:00:00Z
date_available	2012-06-30T00:00:00Z
url	https://revistas.usb.edu.co/index.php/IJPR/article/view/751
url_doi	https://doi.org/10.21500/20112084.751
issn	2011-2084
eissn	2011-7922
doi	10.21500/20112084.751
citationstartpage	52
citationendpage	58
url2_str_mv	https://revistas.usb.edu.co/index.php/IJPR/article/download/751/550
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Genes, the serotonergic system and suicidal behavior

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