Adherencia al tratamiento anticoagulante: Hospital de San José. Bogotá DC, Colombia

La anticoagulación requiere monitoreo continuo por el alto riesgo de complicaciones trombóticas y hemorrágicas. El éxito depende en gran medida de la educación del paciente para una adecuada adherencia terapéutica. Objetivo: evaluar esta adherencia en la clínica de anticoagulación del servicio de hematología del Hospital de San José de Bogotá DC (Colombia) durante un período de tres meses. Metodología: estudio descriptivo de corte transversal en el cual se aplicó la escala ARMS. La puntuación total osciló entre 12 y 48, siendo 12 el nivel perfecto y 48 el peor. Resultados: se aplicó el cuestionario a 106 pacientes. En la evaluación global la puntuación estuvo entre 12 y 26 (promedio: 13.72, DS: 2.19), en la subescala sobre la toma del antic... Ver más

Guardado en:

0121-7372

2462-991X

23

2014-09-01

189

198

http://purl.org/coar/access_right/c_abf2

info:eu-repo/semantics/openAccess

Fundación Universitaria de Ciencias de la Salud FUCS - 0

id 0bf5ae015bc042e631df64bdf65e9d58
record_format ojs
spelling Adherencia al tratamiento anticoagulante: Hospital de San José. Bogotá DC, Colombia
Vitolins MZ RC, Rapp SR, Ribisi PM, Sevick MA. Measuring adherence to behavioral and medical interventions. Control Clin Trials. 2000;21(5):188S-94S.
Limdi NA, Limdi MA, Cavallari L, Anderson AM, Crowley MR, Baird MF, et al. Warfarin dosing in patients with impaired kidney function. Am J Kidney Dis. 2010;56(5):823-31.
Hulse ML. Warfarin resistance: diagnosis and therapeutic alternatives. Pharmacotherapy. 1996;16(6):1009-17.
Hallak HO, Wedlund PJ, Modi MW, Patel IH, Lewis GL, Woodruff B, et al. High clearance of (S)-warfarin in a warfarin-resistant subject. Br J Clin Pharmacol. 1993;35(3):327-30.
Lefrere JJ, Guyon F, Horellou MH, Conard J, Samama M. [Resistance to vitamin K antagonists. 6 cases]. Ann Med Interne (Paris). 1986;137(5):384-90.
Mateo J, Oliver A, Borrell M, Sala N, Fontcuberta J. Laboratory evaluation and clinical characteristics of 2,132 consecutive unselected patients with venous thromboembolism--results of the Spanish Multicentric Study on Thrombophilia (EMET-Study). Thromb Haemost. 1997;77(3):444-51.
Kripalani S RJ, Gatti ME, Jacobson TA. Development and evaluation of the Adherence to Refills and Medications Scale (ARMS) among low-literacy patients with chronic disease. Value Health. 2009;12(1):118-23.
Platt AB, Localio AR, Brensinger CM, Cruess DG, Christie JD, Gross R, et al. Can We Predict Daily Adherence to Warfarin? Chest. 2010;137(4):883-9.
Delaney JA, Opatrny L, Brophy JM, Suissa S. Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding. CMAJ. 2007;177(4):347-51.
Matsui D, Hermann C, Klein J, Berkovitch M, Olivieri N, Koren G. Critical comparison of novel and existing methods of compliance assesment during a clinical trial of an oral iron chelator. J Clin Pharmacol. 1994;34(9):944-9.
Sumartojo E. When tuberculosis treatment fails. A social behavioral account of patient adherence. Am Rev Respir Dis. 1993;147(5):1311-20.
Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24(1):67-74.
Farmer KC. Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice. Clin Ther. 1999;21(6):1074-90.
Timmreck TC, Randolph JF. Smoking cessation: clinical steps to improve compliance. Geriatrics. 1993;48(4):63-6, 9-70.
Rand CS. Measuring adherence with therapy for chronic diseases: implications for the treatment of heterozygous familial hypercholesterolemia. Am J Cardiol. 1993;72(10):68D-74D.
Wysowski DK, Nourjah P, Swartz L. Bleeding complications with warfarin use: a prevalent adverse effect resulting in regulatory action. Arch Intern Med. 2007;167(13):1414-9.
Schelleman H, Bilker WB, Brensinger CM, Wan F, Yang YX, Hennessy S. Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk. Am J Med. 2010;123(2):151-7.
Berrettini M. Anticoagulation clinics: the Italian experience. Haematologica. 1997;82(6):713-7.
http://purl.org/coar/resource_type/c_2df8fbb1
Text
http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
http://purl.org/coar/version/c_970fb48d4fbd8a85
info:eu-repo/semantics/publishedVersion
http://purl.org/redcol/resource_type/ART
http://purl.org/coar/resource_type/c_6501
Limdi NA, Beasley TM, Baird MF, Goldstein JA, McGwin G, Arnett DK, et al. Kidney function influences warfarin responsiveness and hemorrhagic complications. J Am Soc Nephrol. 2009;20(4):912-21.
info:eu-repo/semantics/article
Zhao HJ, Zheng ZT, Wang ZH, Li SH, Zhang Y, Zhong M, et al. “Triple therapy” rather than “triple threat”: a meta-analysis of the two antithrombotic regimens after stent implantation in patients receiving long-term oral anticoagulant treatment. Chest. 2011;139(2):260-70.
Nieto JA, Solano R, Ruiz-Ribo MD, Ruiz-Gimenez N, Prandoni P, Kearon C, et al. Fatal bleeding in patients receiving anticoagulant therapy for venous thromboembolism: findings from the RIETE registry. J Thromb Haemost. 2010 Jun; 8(6):1216-22.
Ruiz-Giménez N, Suárez C, González R, Nieto JA, Todoli JA, Samperiz AL, et al. Predictive variables for major bleeding events in patients presenting with documented acute venous thromboembolism. Findings from the RIETE Registry. Thromb Haemost. 2008;100(1):26-31.
Anand S, Yusuf S, Xie C, Pogue J, Eikelboom J, Budaj A, et al. Oral anticoagulant and antiplatelet therapy and peripheral arterial disease. N Engl J Med.2007;357(3):217-27.
Gage BF, Yan Y, Milligan PE, Waterman AD, Culverhouse R, Rich MW, et al. Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF). Am Heart J. 2006;151(3):713-9.
Wells PS, Forgie MA, Simms M, Greene A, Touchie D, Lewis G, et al. The outpatient bleeding risk index: validation of a tool for predicting bleeding rates in patients treated for deep venous thrombosis and pulmonary embolism. Arch Intern Med. 2003;163(8):917-20.
Van Walraven C, Jennings A, Oake N, Fergusson D, Forster AJ. Effect of study setting on anticoagulation control: a systematic review and metaregression. Chest. 2006;129(5):1155-66.
Wittkowsky AK, Nutescu EA, Blackburn J, Mullins J, Hardman J, Mitchell J, et al. Outcomes of oral anticoagulant therapy managed by telephone vs in-office visits in an anticoagulation clinic setting. Chest. 2006;130(5):1385-9.
Fitzmaurice DA, Hobbs FD, Murray ET, Holder RL, Allan TF, Rose PE. Oral anticoagulation management in primary care with the use of computerized decision support and near-patient testing: a randomized, controlled trial. Arch Intern Med. 2000;160(15):2343-8.
Revista Repertorio de Medicina y Cirugía
La anticoagulación requiere monitoreo continuo por el alto riesgo de complicaciones trombóticas y hemorrágicas. El éxito depende en gran medida de la educación del paciente para una adecuada adherencia terapéutica. Objetivo: evaluar esta adherencia en la clínica de anticoagulación del servicio de hematología del Hospital de San José de Bogotá DC (Colombia) durante un período de tres meses. Metodología: estudio descriptivo de corte transversal en el cual se aplicó la escala ARMS. La puntuación total osciló entre 12 y 48, siendo 12 el nivel perfecto y 48 el peor. Resultados: se aplicó el cuestionario a 106 pacientes. En la evaluación global la puntuación estuvo entre 12 y 26 (promedio: 13.72, DS: 2.19), en la subescala sobre la toma del anticoagulante, entre 8 y 19 (promedio: 9.12, DS: 1.58) y en la subescala según la disponibilidad del medicamento entre 4 y 8 (promedio: 4.60, DS: 1.00). La mejor adherencia se identificó en el ítem 5 (promedio: 1.01, DS: 0.13) y la peor en el ítem 1 (promedio: 1.39, DS: 0.56). El 35% (n= 37) obtuvo una adherencia perfecta. Conclusiones: la adherencia terapéutica global es buena, pero se identificaron barreras relacionadas con el paciente y el suministro del anticoagulante, que justifican el fortalecimiento de la educación al paciente y el desarrollo de estrategias para la entrega oportuna del medicamento.
Solano, Maria Helena
Mendieta, Felipe Andrés
adherencia a la medicación
anticoagulantes
atención ambulatoria
23
3
Núm. 3 , Año 2014 : Julio – Septiembre
Artículo de revista
application/pdf
Sociedad de Cirugía de Bogotá, Hospital de San José y Fundación Universitaria de Ciencias de la Salud
Publication
https://revistas.fucsalud.edu.co/index.php/repertorio/article/view/708
Aziz F, Corder M, Wolffe J, Comerota AJ. Anticoagulation monitoring by an anticoagulation service is more cost-effective than routine physician care. J Vasc Surg. 2011;54(5):1404-7.
Gray DR, Garabedian-Ruffalo SM, Chretien SD. Cost-justification of a clinical pharmacist-managed anticoagulation clinic. Ann Pharmacother. 2007;41(3):496-501.
Chiquette E, Amato MG, Bussey HI. Comparison of an anticoagulation clinic with usual medical care: anticoagulation control, patient outcomes, and health care costs. Arch Intern Med. 1998;158(15):1641-7.
Español
https://creativecommons.org/licenses/by-nc-sa/4.0/
Fundación Universitaria de Ciencias de la Salud FUCS - 0
Nutescu EA. The future of anticoagulation clinics. J Thromb Thrombolysis. 2003;16(1-2):61-3.
ambulatory care
adherence to medication
Adherence to anticoagulant treatment: Hospital de San José. Bogotá DC, Colombia
Anticoagulation requires continuous monitoring because of the high risk of thrombotic and hemorrhagic complications. Success depends to a large extent on the education of the patient for adequate therapeutic adherence. Objective: to evaluate this adherence in the anticoagulation clinic of the hematology service of the San José Hospital of Bogotá DC (Colombia) during a period of three months. Methodology: descriptive cross-sectional study in which the ARMS scale was applied. The total score ranged from 12 to 48, with 12 being the perfect level and 48 the worst. Results: the questionnaire was applied to 106 patients. In the overall evaluation, the score was between 12 and 26 (average: 13.72, SD: 2.19), on the subscale on anticoagulant intake, between 8 and 19 (average: 9.12, DS: 1.58) and on the subscale according to availability of the medicine between 4 and 8 (average: 4.60, DS: 1.00). The best adherence was identified in item 5 (average: 1.01, DS: 0.13) and the worst in item 1 (average: 1.39, DS: 0.56). 35% (n = 37) obtained a perfect adhesion. Conclusions: the overall therapeutic adherence is good, but barriers related to the patient and the anticoagulant supply were identified, which justify the strengthening of patient education and the development of strategies for the timely delivery of the medication.
Journal article
anticoagulants
198
0121-7372
189
https://revistas.fucsalud.edu.co/index.php/repertorio/article/download/708/749
2462-991X
https://doi.org/10.31260/RepertMedCir.v23.n3.2014.708
2014-09-01T00:00:00Z
2014-09-01T00:00:00Z
10.31260/RepertMedCir.v23.n3.2014.708
2014-09-01
institution FUNDACIÓN UNIVERSITARIA DE CIENCIA DE LA SALUD
thumbnail https://nuevo.metarevistas.org/FUNDACIONUNIVERSITARIADECIENCIADELASALUD/logo.png
country_str Colombia
collection Revista Repertorio de Medicina y Cirugía
title Adherencia al tratamiento anticoagulante: Hospital de San José. Bogotá DC, Colombia
spellingShingle Adherencia al tratamiento anticoagulante: Hospital de San José. Bogotá DC, Colombia
Solano, Maria Helena
Mendieta, Felipe Andrés
adherencia a la medicación
anticoagulantes
atención ambulatoria
ambulatory care
adherence to medication
anticoagulants
title_short Adherencia al tratamiento anticoagulante: Hospital de San José. Bogotá DC, Colombia
title_full Adherencia al tratamiento anticoagulante: Hospital de San José. Bogotá DC, Colombia
title_fullStr Adherencia al tratamiento anticoagulante: Hospital de San José. Bogotá DC, Colombia
title_full_unstemmed Adherencia al tratamiento anticoagulante: Hospital de San José. Bogotá DC, Colombia
title_sort adherencia al tratamiento anticoagulante: hospital de san josé. bogotá dc, colombia
title_eng Adherence to anticoagulant treatment: Hospital de San José. Bogotá DC, Colombia
description La anticoagulación requiere monitoreo continuo por el alto riesgo de complicaciones trombóticas y hemorrágicas. El éxito depende en gran medida de la educación del paciente para una adecuada adherencia terapéutica. Objetivo: evaluar esta adherencia en la clínica de anticoagulación del servicio de hematología del Hospital de San José de Bogotá DC (Colombia) durante un período de tres meses. Metodología: estudio descriptivo de corte transversal en el cual se aplicó la escala ARMS. La puntuación total osciló entre 12 y 48, siendo 12 el nivel perfecto y 48 el peor. Resultados: se aplicó el cuestionario a 106 pacientes. En la evaluación global la puntuación estuvo entre 12 y 26 (promedio: 13.72, DS: 2.19), en la subescala sobre la toma del anticoagulante, entre 8 y 19 (promedio: 9.12, DS: 1.58) y en la subescala según la disponibilidad del medicamento entre 4 y 8 (promedio: 4.60, DS: 1.00). La mejor adherencia se identificó en el ítem 5 (promedio: 1.01, DS: 0.13) y la peor en el ítem 1 (promedio: 1.39, DS: 0.56). El 35% (n= 37) obtuvo una adherencia perfecta. Conclusiones: la adherencia terapéutica global es buena, pero se identificaron barreras relacionadas con el paciente y el suministro del anticoagulante, que justifican el fortalecimiento de la educación al paciente y el desarrollo de estrategias para la entrega oportuna del medicamento.
description_eng Anticoagulation requires continuous monitoring because of the high risk of thrombotic and hemorrhagic complications. Success depends to a large extent on the education of the patient for adequate therapeutic adherence. Objective: to evaluate this adherence in the anticoagulation clinic of the hematology service of the San José Hospital of Bogotá DC (Colombia) during a period of three months. Methodology: descriptive cross-sectional study in which the ARMS scale was applied. The total score ranged from 12 to 48, with 12 being the perfect level and 48 the worst. Results: the questionnaire was applied to 106 patients. In the overall evaluation, the score was between 12 and 26 (average: 13.72, SD: 2.19), on the subscale on anticoagulant intake, between 8 and 19 (average: 9.12, DS: 1.58) and on the subscale according to availability of the medicine between 4 and 8 (average: 4.60, DS: 1.00). The best adherence was identified in item 5 (average: 1.01, DS: 0.13) and the worst in item 1 (average: 1.39, DS: 0.56). 35% (n = 37) obtained a perfect adhesion. Conclusions: the overall therapeutic adherence is good, but barriers related to the patient and the anticoagulant supply were identified, which justify the strengthening of patient education and the development of strategies for the timely delivery of the medication.
author Solano, Maria Helena
Mendieta, Felipe Andrés
author_facet Solano, Maria Helena
Mendieta, Felipe Andrés
topicspa_str_mv adherencia a la medicación
anticoagulantes
atención ambulatoria
topic adherencia a la medicación
anticoagulantes
atención ambulatoria
ambulatory care
adherence to medication
anticoagulants
topic_facet adherencia a la medicación
anticoagulantes
atención ambulatoria
ambulatory care
adherence to medication
anticoagulants
citationvolume 23
citationissue 3
citationedition Núm. 3 , Año 2014 : Julio – Septiembre
publisher Sociedad de Cirugía de Bogotá, Hospital de San José y Fundación Universitaria de Ciencias de la Salud
ispartofjournal Revista Repertorio de Medicina y Cirugía
source https://revistas.fucsalud.edu.co/index.php/repertorio/article/view/708
language Español
format Article
rights http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/4.0/
Fundación Universitaria de Ciencias de la Salud FUCS - 0
references Vitolins MZ RC, Rapp SR, Ribisi PM, Sevick MA. Measuring adherence to behavioral and medical interventions. Control Clin Trials. 2000;21(5):188S-94S.
Limdi NA, Limdi MA, Cavallari L, Anderson AM, Crowley MR, Baird MF, et al. Warfarin dosing in patients with impaired kidney function. Am J Kidney Dis. 2010;56(5):823-31.
Hulse ML. Warfarin resistance: diagnosis and therapeutic alternatives. Pharmacotherapy. 1996;16(6):1009-17.
Hallak HO, Wedlund PJ, Modi MW, Patel IH, Lewis GL, Woodruff B, et al. High clearance of (S)-warfarin in a warfarin-resistant subject. Br J Clin Pharmacol. 1993;35(3):327-30.
Lefrere JJ, Guyon F, Horellou MH, Conard J, Samama M. [Resistance to vitamin K antagonists. 6 cases]. Ann Med Interne (Paris). 1986;137(5):384-90.
Mateo J, Oliver A, Borrell M, Sala N, Fontcuberta J. Laboratory evaluation and clinical characteristics of 2,132 consecutive unselected patients with venous thromboembolism--results of the Spanish Multicentric Study on Thrombophilia (EMET-Study). Thromb Haemost. 1997;77(3):444-51.
Kripalani S RJ, Gatti ME, Jacobson TA. Development and evaluation of the Adherence to Refills and Medications Scale (ARMS) among low-literacy patients with chronic disease. Value Health. 2009;12(1):118-23.
Platt AB, Localio AR, Brensinger CM, Cruess DG, Christie JD, Gross R, et al. Can We Predict Daily Adherence to Warfarin? Chest. 2010;137(4):883-9.
Delaney JA, Opatrny L, Brophy JM, Suissa S. Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding. CMAJ. 2007;177(4):347-51.
Matsui D, Hermann C, Klein J, Berkovitch M, Olivieri N, Koren G. Critical comparison of novel and existing methods of compliance assesment during a clinical trial of an oral iron chelator. J Clin Pharmacol. 1994;34(9):944-9.
Sumartojo E. When tuberculosis treatment fails. A social behavioral account of patient adherence. Am Rev Respir Dis. 1993;147(5):1311-20.
Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24(1):67-74.
Farmer KC. Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice. Clin Ther. 1999;21(6):1074-90.
Timmreck TC, Randolph JF. Smoking cessation: clinical steps to improve compliance. Geriatrics. 1993;48(4):63-6, 9-70.
Rand CS. Measuring adherence with therapy for chronic diseases: implications for the treatment of heterozygous familial hypercholesterolemia. Am J Cardiol. 1993;72(10):68D-74D.
Wysowski DK, Nourjah P, Swartz L. Bleeding complications with warfarin use: a prevalent adverse effect resulting in regulatory action. Arch Intern Med. 2007;167(13):1414-9.
Schelleman H, Bilker WB, Brensinger CM, Wan F, Yang YX, Hennessy S. Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk. Am J Med. 2010;123(2):151-7.
Berrettini M. Anticoagulation clinics: the Italian experience. Haematologica. 1997;82(6):713-7.
Limdi NA, Beasley TM, Baird MF, Goldstein JA, McGwin G, Arnett DK, et al. Kidney function influences warfarin responsiveness and hemorrhagic complications. J Am Soc Nephrol. 2009;20(4):912-21.
Zhao HJ, Zheng ZT, Wang ZH, Li SH, Zhang Y, Zhong M, et al. “Triple therapy” rather than “triple threat”: a meta-analysis of the two antithrombotic regimens after stent implantation in patients receiving long-term oral anticoagulant treatment. Chest. 2011;139(2):260-70.
Nieto JA, Solano R, Ruiz-Ribo MD, Ruiz-Gimenez N, Prandoni P, Kearon C, et al. Fatal bleeding in patients receiving anticoagulant therapy for venous thromboembolism: findings from the RIETE registry. J Thromb Haemost. 2010 Jun; 8(6):1216-22.
Ruiz-Giménez N, Suárez C, González R, Nieto JA, Todoli JA, Samperiz AL, et al. Predictive variables for major bleeding events in patients presenting with documented acute venous thromboembolism. Findings from the RIETE Registry. Thromb Haemost. 2008;100(1):26-31.
Anand S, Yusuf S, Xie C, Pogue J, Eikelboom J, Budaj A, et al. Oral anticoagulant and antiplatelet therapy and peripheral arterial disease. N Engl J Med.2007;357(3):217-27.
Gage BF, Yan Y, Milligan PE, Waterman AD, Culverhouse R, Rich MW, et al. Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF). Am Heart J. 2006;151(3):713-9.
Wells PS, Forgie MA, Simms M, Greene A, Touchie D, Lewis G, et al. The outpatient bleeding risk index: validation of a tool for predicting bleeding rates in patients treated for deep venous thrombosis and pulmonary embolism. Arch Intern Med. 2003;163(8):917-20.
Van Walraven C, Jennings A, Oake N, Fergusson D, Forster AJ. Effect of study setting on anticoagulation control: a systematic review and metaregression. Chest. 2006;129(5):1155-66.
Wittkowsky AK, Nutescu EA, Blackburn J, Mullins J, Hardman J, Mitchell J, et al. Outcomes of oral anticoagulant therapy managed by telephone vs in-office visits in an anticoagulation clinic setting. Chest. 2006;130(5):1385-9.
Fitzmaurice DA, Hobbs FD, Murray ET, Holder RL, Allan TF, Rose PE. Oral anticoagulation management in primary care with the use of computerized decision support and near-patient testing: a randomized, controlled trial. Arch Intern Med. 2000;160(15):2343-8.
Aziz F, Corder M, Wolffe J, Comerota AJ. Anticoagulation monitoring by an anticoagulation service is more cost-effective than routine physician care. J Vasc Surg. 2011;54(5):1404-7.
Gray DR, Garabedian-Ruffalo SM, Chretien SD. Cost-justification of a clinical pharmacist-managed anticoagulation clinic. Ann Pharmacother. 2007;41(3):496-501.
Chiquette E, Amato MG, Bussey HI. Comparison of an anticoagulation clinic with usual medical care: anticoagulation control, patient outcomes, and health care costs. Arch Intern Med. 1998;158(15):1641-7.
Nutescu EA. The future of anticoagulation clinics. J Thromb Thrombolysis. 2003;16(1-2):61-3.
type_driver info:eu-repo/semantics/article
type_coar http://purl.org/coar/resource_type/c_2df8fbb1
type_version info:eu-repo/semantics/publishedVersion
type_coarversion http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content Text
publishDate 2014-09-01
date_accessioned 2014-09-01T00:00:00Z
date_available 2014-09-01T00:00:00Z
url https://revistas.fucsalud.edu.co/index.php/repertorio/article/view/708
url_doi https://doi.org/10.31260/RepertMedCir.v23.n3.2014.708
issn 0121-7372
eissn 2462-991X
doi 10.31260/RepertMedCir.v23.n3.2014.708
citationstartpage 189
citationendpage 198
url2_str_mv https://revistas.fucsalud.edu.co/index.php/repertorio/article/download/708/749
_version_ 1797159736460705792